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DHA in Pregnancy Not Linked to Atopic Diseases in High-Risk Children at Age 3

There are many plausible reasons to think that increased consumption of long-chain omega-3 PUFAs (n-3 LC-PUFAs) during pregnancy or infancy may reduce the development of atopic allergic diseases, such...

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Reference Profiles for PUFA-derived Lipid Mediators in Human Plasma and Serum

The long chain polyunsaturated fatty acids (PUFA) arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) are used by the body to produce lipid mediators, which are...

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Circulating Specialized Proresolving Lipid Mediators after Short-term...

This article at a glance This study addressed the levels of anti-inflammatory and resolution-promoting lipid mediators derived from EPA and DHA in human plasma during oral supplementation with EPA/DHA...

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EPA for Remission of Autoimmune Small-Vessel Vasculitis

This article at a glance In two clinical cases, EPA was recognized to possibly offer support to the long-term remission of autoimmune small vessel vasculitis, when used in combination with...

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Short-term Perioperative EPA/DHA Supplementation for Immune Modulation and...

This article at a glance Three recent studies have looked at different aspects of early post-surgical immune-modulatory effects of perioperative supplementation with EPA/DHA. These include lowered...

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Modulation of the Acute Phase Response by Polyunsaturated Fatty Acids in...

This article at a glance Two recently published studies report on the relations between dietary intake and levels of poly-unsaturated fatty acids (PUFA) in blood and the acute phase response C-reactive...

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Making PUFAs Available for Tissue Protection – Selective...

This article at a glance A recent study in mice reports that human and mouse secretory group X phospholipase A2 preferentially releases omega-3 long-chain polyunsaturated fatty acids to serve...

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Regulation of B-cell IgE Production by a DHA-Derived Lipid Mediator

This article at a glance This study assessed the effect of DHA-derived lipid mediators on IgE formation by B-lymphocytes, an important component of the adaptive immune system that is activated in...

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The Impact of Omega-3 LCPUFA on Colorectal Cancer Development Guides Clinical...

This article at a glance In adults that develop colorectal cancer, survival is increased if omega-3 LCPUFA intake is modestly increased after diagnosis. Large prospective cohort studies tracked...

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The Development of Chemoresistance: A New Immune Cell-Activating Mechanism...

This article at a glance This study identifies the omega-3 polyunsaturated fatty acid hexadecatetraenoic acid (16:4 n-3) as a ligand of GPR120, a receptor studied for its role in regulating...

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Eicosapentaenoic Acid and Docosahexaenoic Acid: Are They Different?

Trevor A Mori, Ph.D., Professor, School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia, Perth, Australia. Many of the cardiovascular benefits ascribed to...

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DHA in Pregnancy Not Linked to Atopic Diseases in High-Risk Children at Age 3

There are many plausible reasons to think that increased consumption of long-chain omega-3 PUFAs (n-3 LC-PUFAs) during pregnancy or infancy may reduce the development of atopic allergic diseases, such...

View Article

Reference Profiles for PUFA-derived Lipid Mediators in Human Plasma and Serum

The long chain polyunsaturated fatty acids (PUFA) arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) are used by the body to produce lipid mediators, which are...

View Article


Circulating Specialized Proresolving Lipid Mediators after Short-term...

This article at a glance This study addressed the levels of anti-inflammatory and resolution-promoting lipid mediators derived from EPA and DHA in human plasma during oral supplementation with EPA/DHA...

View Article

EPA for Remission of Autoimmune Small-Vessel Vasculitis

This article at a glance In two clinical cases, EPA was recognized to possibly offer support to the long-term remission of autoimmune small vessel vasculitis, when used in combination with...

View Article


Short-term Perioperative EPA/DHA Supplementation for Immune Modulation and...

This article at a glance Three recent studies have looked at different aspects of early post-surgical immune-modulatory effects of perioperative supplementation with EPA/DHA. These include lowered...

View Article

Modulation of the Acute Phase Response by Polyunsaturated Fatty Acids in...

This article at a glance Two recently published studies report on the relations between dietary intake and levels of poly-unsaturated fatty acids (PUFA) in blood and the acute phase response C-reactive...

View Article


Making PUFAs Available for Tissue Protection – Selective...

This article at a glance A recent study in mice reports that human and mouse secretory group X phospholipase A2 preferentially releases omega-3 long-chain polyunsaturated fatty acids to serve...

View Article

Regulation of B-cell IgE Production by a DHA-Derived Lipid Mediator

This article at a glance This study assessed the effect of DHA-derived lipid mediators on IgE formation by B-lymphocytes, an important component of the adaptive immune system that is activated in...

View Article

The Impact of Omega-3 LCPUFA on Colorectal Cancer Development Guides Clinical...

This article at a glance In adults that develop colorectal cancer, survival is increased if omega-3 LCPUFA intake is modestly increased after diagnosis. Large prospective cohort studies tracked...

View Article
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